Found 15 matching trials
JZP458 - Recombinant Erwinia Asparaginase for Treatment of ALL / LBL Patients With Hypersensitivity to E. Coli-derived Asparaginase N/A This study is an Expanded Access Protocol (EAP) of JZP458 in participants w...
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Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL) PHASE1 H. Lee Moffitt Cancer Center and Research Institute will be the Sunshine Pr...
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Holtz Children's Hospital University of Miami Miller School of Medicine
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Asparaginase Encapsulated in Erythrocytes for Patients With ALL and Hypersensitivity to PEG-asparaginase PHASE2 Pegylated-asparaginase (PEG-ASP) is an important part of the treatment of c...
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Aahus University hospial, hematological department
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Forecasting Hypersensitivity Against PEG-asparaginase to Optimize Outcome in ALL N/A Asparaginase is a cornerstone in the treatment of acute lymphoblastic leuke...
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Aarhus University Hospital
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A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL PHASE2 This prospective, randomized, multicenter, open-label Phase 2 study is desi...
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St. Anna Kinderspital
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UNDERSTANDING THE T-CELL AND B-CELL RECEPTOR REPERTOIRE IN CHILDREN AND YOUNG ADULTS WITH ANTI-DRUG ANTIBODIES AGAINST PEG ASPARAGINASE N/A The aim of this sub study is to identify biomarkers in children and young a...
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Multiple Locations
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Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL) PHASE3 B-precursor ALL is an aggressive malignant disease. Therapy is usually stra...
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An Open-Label Study of JZP-458 (RC-P) in Patients With Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL) PHASE2 This is an open-label, multicenter, dose confirmation, and PK study of JZP-...
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Children's of Alabama
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Role of T Lymphocytes in Hypersensitivity Reactions to Asparaginase in Patients Treated for Acute Lymphoblastic Leukemia. NA Acute lymphoblastic leukemia is a type of blood cancer that primarily affec...
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Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017 PHASE3 The understanding of acute lymphoblastic leukemia (ALL) in childhood and ad...
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Sydney Children's Hospital
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